Pharmacology Proctored ATI Practice Exam

Which medication should the nurse administer prior to a transfusion to a client who had a mild allergic reaction during a previous transfusion?

1. Diphenhydramine

2. Acetaminophen

3. Ibuprofen

4. Prednisone

The correct answer is: Diphenhydramine

Diphenhydramine is the most appropriate medication to administer prior to a transfusion to a client who has had a previous mild allergic reaction during a transfusion. This is because Diphenhydramine is an antihistamine that can help prevent an allergic reaction from occurring by blocking the release of histamine. This medication is specifically used to treat allergic reactions and is considered safe to use before a transfusion. Additionally, Acetaminophen and Ibuprofen are pain relievers and not used for preventing allergic reactions. Prednisone, while also used for allergic reactions, should not be administered prior to a transfusion as it can weaken the immune system and increase the risk of infection.